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What (who) is MIB1 - definition
MIB1
HUMAN ENZYME
MIB1 (gene)
E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene. It is involved in regulating apoptosis.
Ki-67 (protein)
![High Ki-67 expression in an invasive [[breast cancer]], with cancer nuclei being stained (brown). There is tumor cell positivity in 70% of the cells:''Ki-67 labelling index'' = 70%](https://commons.wikimedia.org/wiki/Special:FilePath/Positive immunohistochemistry of KI-67 in invasive breast cancer.jpg?width=200 "High Ki-67 expression in an invasive [[breast cancer]], with cancer nuclei being stained (brown). There is tumor cell positivity in 70% of the cells:''Ki-67 labelling index'' = 70%")
![Immunofluorescent antibody staining against neurofilament (green) and Ki-67 (red) in a mouse embryo 12.5 days after fertilization. The proliferating cells are in the ventricular zone in the [[neural tube]] and therefore colored red.](https://commons.wikimedia.org/wiki/Special:FilePath/Mouse NT antibody NF Ki67.jpg?width=200 "Immunofluorescent antibody staining against neurofilament (green) and Ki-67 (red) in a mouse embryo 12.5 days after fertilization. The proliferating cells are in the ventricular zone in the [[neural tube]] and therefore colored red.")
![Ki-67 protein (red), [[tubulin]] (green) and DNA (blue) in HeLa cells. Dividing cells show strong Ki-67 staining in cell nuclei while all cells contain large amounts of tubulin, the major component of [[microtubules]]. Antibodies, cell staining and image courtesy of [[EnCor Biotechnology]].](https://commons.wikimedia.org/wiki/Special:FilePath/Ki67-Tubulin.jpg?width=200 "Ki-67 protein (red), [[tubulin]] (green) and DNA (blue) in HeLa cells. Dividing cells show strong Ki-67 staining in cell nuclei while all cells contain large amounts of tubulin, the major component of [[microtubules]]. Antibodies, cell staining and image courtesy of [[EnCor Biotechnology]].")
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Ki-67/MIB1; Ki-67 antigen; Antigen identified by monoclonal antibody Ki-67; MKI67; Ki-67 (Biology); Ki67; Ki-67 (biology); MKI67 (gene); Ki–67 index; Ki-67 index
Antigen KI-67, also known as Ki-67, Ki-67 or MKI67 (Marker Of Proliferation Ki-67), is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal antibody Ki-67).
